Coca-Cola Zero

Coca-Cola Zero Sugar is a zero-calorie, sugar-free version of the classic cola, sweetened with aspartame and acesulfame K rather than sugar ^[1][2]. This matters for gout because fructose — from table sugar and high-fructose corn syrup — raises uric acid production, and Coke Zero contains none of it. The drink also has no purines and no alcohol, so it adds no direct uric acid load.

The main things to weigh are caffeine and acidity. Each serving contains caffeine from the flavorings ^[2]. Caffeine is not a strong trigger for most people with gout, and some research even suggests it may modestly lower uric acid, but those sensitive to caffeine should monitor intake. The phosphoric acid that gives cola its tang ^[2] can be hard on kidneys in large quantities, and since gout often coexists with impaired kidney function, it is wise to keep consumption moderate.

Practical guidance: Coke Zero is fine for gout as an occasional treat and a far better choice than sugared sodas, which spike uric acid via fructose. It should not replace water — staying well hydrated helps the kidneys flush uric acid. Note it contains phenylalanine, which only matters for people with PKU ^[3].