Brandy and cola combines alcohol with sugar-sweetened soda — both raise uric acid and trigger gout flares.
Brandy and cola is a double threat for people with gout because both ingredients independently raise uric acid. Brandy is a distilled spirit — and spirits (like all alcoholic drinks) increase uric acid production and reduce how well your kidneys clear uric acid, which can rapidly trigger a flare in sensitive individuals. Cola, when sweetened with sugar (sucrose) or high-fructose corn syrup, delivers a large fructose load. Fructose is metabolized in the liver and directly drives up uric acid production, and it also competes with uric acid for excretion through the kidneys.
The combination is synergistic: alcohol dehydrates you while fructose spikes uric acid, and both blunt the kidney's ability to eliminate uric acid. A single mixed drink can raise serum urate within hours, and multiple servings (common with this style of drink) compound the effect.
AI-researched information — not medical advice. Ask a qualified clinician before changing your diet or treatment.